Chemical Microarray-Based Drug Screening Service

As a leading supplier in the field of microarrays, CD Genomics is committed to designing and developing various effective biological microarray products for non-clinical research and providing corresponding testing services. Our microarray test platform provides a full range of microarray-based analysis and measurement services for obtaining three-dimensional information in pathophysiology research to help our global customers conduct related research and reduce research costs. We are confident to provide you with high-quality products and high-quality services to help scientific research.

Chemical Compound Microarray and Drug Discovery

The study of the interaction between chemical compounds and biological targets dominates modern drug discovery research. Genomics and proteomics studies have shown that there may be more than 10,000 pharmacologically treatable targets. However, less than 5% of these targets have corresponding approved drugs. Therefore, it has become one of the most challenging tasks in today's drug discovery process to screen a large number of chemical substances for new targets in a fast and economical way to find candidate drugs. In order to further increase throughput and reduce the cost of chemicals and targets, the miniaturization of bioassays has become a trend in today's assay development and laboratory automation. The success of microarray technology in genomics and proteomics research has provided new impetus for miniaturization and has provided unprecedented possibilities and capabilities for parallel functional analysis of hundreds or even thousands of biological entities.

Service

This is a combined chip service for theanalysis of chemicals, such as polysaccharides, terpenes, steroids, alkaloids,and ketones. Using the principle of the reversed-phase array, the target isbuilt into a library, and then the microarray is made by chemical synthesis.Afterward, potential targets were screened out using microarray hybridization,and mass spectrometry and other means were used for further structuralanalysis. This service can also target the discovery of new indications forexisting compounds and drug groups. The probe set is selected and designed fromthe database of target structure information.

Fig 1. Drug discovery services based on chemical microarrays.

Our Benefits

• Used to analyze biological events caused by medicines and predict the therapeutic potential of medicines;
• Evaluate the safety of medicines and identify drug candidates;
• Identify phytochemical candidates for drug development;
• Use large-scale gene expression analysis of toxin-treated cells and animals to identify the potential toxicity of new drug candidates;
• The advantage of choosing combination analysis is that you can get discounts;
• Accelerate the research through high-throughput screening methods;

CD Genomics provides high-quality compound microarray tools and convenient detection services. We have a large and well-equipped team of scientists who are committed to cooperating with researchers from all over the world. By choosing outsourcing testing services, your advantage is that you do not need to consider any other expenses, such as equipment, laboratory space, supervision or management. This convenient method can quickly turn around and provide reliable results, thus saving valuable time and resources. Please contact us for more detailed information.

References

1. Kijanka G, Murphy D. Protein arrays as tools for serum autoantibody marker discovery in cancer[J]. Journal of proteomics, 2009, 72(6): 936-944.
2. Tanase C, Albulescu R, Neagu M. Proteomic approaches for biomarker panels in cancer[J]. Journal of Immunoassay and Immunochemistry, 2016, 37(1): 1-15.