CD Genomics is a world-leading company that can provide the best microarray products and solutions for global customers in the field of transcriptomics research. We have successfully completed many related microarray projects and can provide the best products and services to customers all over the world.
Bio-microarray has designed an optimized promoter methylation microarray. Based on the ChIP-on-chip method, the position analysis of human DNA methylation binding proteins is performed using ChIP-validated probes on the chip. Promoters are an important part of expression vectors because they control the binding of RNA polymerase to DNA. RNA polymerase transcribes DNA into mRNA and finally translates it into a functional protein. Therefore, the promoter region controls the expression time and location of the gene of interest in the organism. More and more studies have shown that there is a reverse interaction mechanism between promoter methylation and gene expression activity. Studies have found that up to 3% to 6% of cytosines in the human genome are methylated, and methylation has become an important factor affecting gene expression. Many current studies have shown that abnormal methylation of CpG islands in the promoter region of tumor suppressor genes leads to a variety of tumors.
Our promoter microarrays include but are not limited to humans and mice. Our human promoter microarray is specially designed for the location analysis of human DNA binding protein sites. This microarray targets approximately 21,000 of the most specific human genes represented by RefSeq at different resolutions. The mouse promoter microarray is validated using ChIP-on-chip technology and is designed for the location analysis of mouse DNA-binding proteins, with probes targeting approximately 19,000 genes.
If you have other species of interest, you can contact our expert team to customize the microarray. In addition, we also provide professional software of GenomeStudio methylation software, which can promote the personalized analysis of scientific researchers.
CD Genomics provides high-quality array products and services for epigenetics and methylation modification research. With a large team of scientists and a well-equipped test platform, we are committed to cooperating with customers all over the world to meet your specific requirements. We have comprehensive design and production capabilities to provide broad and comprehensive services for academic and industrial research. If you are interested in our services, please contact us for more details.
|+ CDME-4||Human Promoter Microarray||Online Inquiry|
Description: Human promoter microarrays are specifically designed for location analysis of human DNA-binding protein sites. The human promoter microarrays are targeting ~21,000 of the best-defined human genes as represented by RefSeq at different resolutions.
|+ CDME-5||Mouse Promoter Microarray||Online Inquiry|
Description: Mouse promoter microarrays are optimized using probes validated for ChIP-on-chip technology targeting approximately 19000 genes. These mouse promoter DNA arrays are specifically designed for location analysis of mouse DNA-binding proteins.