CD Genomics is a leading global company who can provide the best solution for worldwide customers in the field of DNA microarray. We have successfully accomplished many projects in DNA microarray for genotyping. We guarantee the finest results for our customers all over the world.
Single nucleotide polymorphisms (SNPs) are DNA sequence polymorphisms caused by single nucleotide alteration (including transition, transversion, deletion and insertion). As a third generation genetic marker, SNP is an ideal genotyping target because of its large number, wide distribution and easy detection features. SNP detection has been widely used in many fields, such as identifying disease susceptibility genes, marker development, gene mapping and population genetics. SNP typing is of great significance in disease genome, genetic breeding, population evolution, pharmacogenomics, diagnostics, biomedical research and other fields1. Compared with NGS sequencing, SNP microarray has a lower price, faster speed, and more stability. CD Genomics provides Human Whole-genome Genotyping Microarray and Human Exome Microarray, which can be used in applications such as genome-wide polymorphism scanning, genome-wide association analysis, family linkage analysis, population evolution analysis, etc. In addition, some loci in the disease database and drug metabolism database are also included in our microarrays, which can support the susceptibility loci screening. Our high-throughput human SNP microarray is suitable for genome-wide SNP typing and gene copy number change research. One single chip can detect hundreds of thousands of labeled SNP loci and provide large-scale disease gene scanning. We adopt the TagSNP design published in the HAPMAP database, which has incomparable coverage advantages. It can detect 4, 8 or 12 samples at the same time. It can also increase the number of customized loci and arbitrary loci. It can detect up to 5 million SNP loci, and ensure high-quality experimental results. Our microarrays cover global human races and genotyping chips are economical for transformation research. Our human microarrays referenced the sequencing results of the 1000 genomes project (1KG), selecting information about functional variation, known association sites, pharmacogenomics, and exon content. Our human microarrays are suitable for carrying out multi-races, large-scale genome-wide association studies (GWAS), risk screening, precision medical projects, as well as a variety of common diseases (such as type II diabetes, cancer, metabolic and psychiatric diseases) and so on.
DNA Sample requirements
- Amount: no less than 1 ug for each sample;
- Concentration: 0.5-50ng/µl;
- Purity: OD 260/280 should be 1.7 ~ 1.9;
- Quality: genome should be integral, no degradation, no RNA contamination or other genomic DNA contamination;
- Preservation and transportation: samples should be transported at low temperature (- 20℃) and sealed with sealing film to prevent contamination.
CD Genomics offers high-quality services in genome SNP genotyping. We can provide commercial chips, customized chips and semi-customized chip services of Human DNA SNP Microarray. With a large and well-equipped scientist team, we are dedicated to collaborating with our clients around the world to meet your specific requirements. We have comprehensive capacity and capabilities to provide a broad and integrated portfolio of laboratory and manufacturing services. If you are interested in our services, please contact us for more details.
Reference
- Gunderson K L, et al. (2005). "A genome-wide scalable SNP genotyping assay using microarray technology." Nature Genetics, 37 (5), 549-554.
